Exercise-Induced Hypoalgesia Differences Between Upper and Lower Limbs Resistance Training Interventions

Centro Universitario La Salle

Status: Enrolling

Conditions: Local Hypoalgesia; Distal Hypoalgesia; Pressure Pain Thresholds; Resistance Training

Treatments: Other: Lower limb resistance training; Other: Upper limb resistance training

Study type: Interventional

Funder types: Other

Identifiers

NCT06765486

CSEULS-PI-013

Details and patient eligibility

About

This randomized controlled trial with healthy subjects aims to compare exercise-induced hypoalgesia among three groups: one utilizing a lower limb resistance training intervention, another using an upper limb resistance training, and a control group. The exercise protocol involves 3 sets of 5 repetitions of resistance exercises (brachial biceps curl and leg extensions). Exercise-induced hypoalgesia will be assessed by measuring pressure pain thresholds in the thigh and elbow, comparing exercise interventions with the control group. Additionally, a secondary objective is to compare the lower limb and upper limb resistance training groups in terms of their effects on pressure pain thresholds in the thigh and elbow. Thus, the study anticipates observing differences in local and distal hypoalgesia based on the trained region.

Enrollment: 90 estimated patients

Sex: All

Ages: 18 to 64 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Asymptomatic subjects aged between 18 and 64 years.

Exclusion criteria

• Cardiovascular, respiratory, metabolic, neurological, or osteomuscular signs or pathologies.
• History of epilepsy.
• Pregnant.
• Participants who present any type of pain on the day of the measurements or who have frequently suffered pain during the previous 12 weeks.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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90 participants in 3 patient groups

Lower limb resistance training

Experimental group

Description:

The participants in the lower limb resistance training group will undergo 3 sets of 5 repetitions of leg extensions with the 5-resistance maximum (5RM), comprising a 5-minute warm-up in cycle ergometer at 1 watt per kg and 60-80 revolutions per minute and 1 set of 5 repetitions with the 10-resistance maximum (10RM).

Treatment:

Other: Lower limb resistance training

Upper limb resistance training

Experimental group

Description:

The participants in the upper limb resistance training group will undergo 3 sets of 5 repetitions of brachial biceps curl with the 5RM, comprising a 5-minute warm-up in cycle ergometer at 1 watt per kg and 60-80 revolutions per minute and 1 set of 5 repetitions with the 10RM.

Treatment:

Other: Upper limb resistance training

Control

No Intervention group

Description:

Participants in the control group will remain seated for the entire duration of the experiment without receiving any form of distraction.