Exercise Intensity and Appetite in Adolescents

U

Université Blaise Pascal, Clermont-Ferrand

Status

Unknown

Conditions

Pediatric Obesity

Treatments

Behavioral: acute exercise

Study type

Interventional

Funder types

Other

Identifiers

NCT02484612
AME2P Laboratory

Details and patient eligibility

About

Acute exercise has been shown to affect subsequent energy intake in obese adolescents. Indeed, it has been shown several times that an intensive bout of exercise (above 70% of the individual maximal capacities) can reduce energy intake at the following meal in obese adolescents, with no modification of his appetite feelings. Although this results has been replicated several times, it remains unknown if those nutritional adaptations are due to post-exercise modifications of some gastro-peptides implicated in appetite control, as detailed in adults. The aim of this work is to question whether or not post-exercise energy intake is explained by appetite-regulating hormones that are affected by the exercise bout in both lean and obese youth.

Full description

After an first medical visit to ensure that the adolescents have the ability to complete the whole study, the participants will have to complete several clinical examinations: anthropometric measurements Body composition assessed by dual energy x-ray absorptiometry Maximal aerobic test They will then randomly complete the following conditions: CON: a control day without exercise; HIE: an exercise day with an exercise set at 75% of the capacities LIE: an exercise day with an exercise set at 40% of the capacities The exercises or the rest condition will be done by the end of the morning and a buffet meal will be proposed during which the participants will be asked to eat as much as wanted. Blood samples will be drawn before, after, 15 after and 30 minutes after the exercise to assess the main appetite regulating hormones involved in appetite regulation (PYY, Cholecystokinin ...) appetite feelings will be assessed throughout the day at regular interval using visual analogue scales.

Enrollment

30 estimated patients

Sex

Male

Ages

12 to 15 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • 12 to 15 years old adolescents
  • Obese according to international values for BMI
  • Being registered to the national social security insurance
  • no eating disorders
  • no medications
  • metabolic disorders

Exclusion criteria

  • metabolic disorders
  • food disorders
  • physical disability

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Factorial Assignment

Masking

None (Open label)

30 participants in 2 patient groups

Lean adolescents
Experimental group
Description:
15 lean adolescents (BMI Under the national cut-offs for obesity), 12-15 years old, males, will be recruited
Treatment:
Behavioral: acute exercise
Obese adolescents
Experimental group
Description:
15 obese adolescents (BMI above the national cut-offs for obesity), 12-15 years old, males, will be recruited
Treatment:
Behavioral: acute exercise

Trial contacts and locations

0

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location

Resources

© Copyright 2024 Veeva Systems