Exercise Intervention in Breast Cancer Patients With Treatment-Induced Arthralgia

Roswell Park Comprehensive Cancer Center

Status: Completed

Conditions: Breast Cancer; Arthralgia

Treatments: Behavioral: Exercising block

Study type: Interventional

Funder types: Other

Identifiers

NCT01236417

I 169310

Details and patient eligibility

About

This is a pilot study of a specifically designed exercise intervention developed for breast cancer patients with aromatase-inhibitor related joint pain.

Enrollment: 27 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Post menopausal women with a history of estrogen positive breast cancer who are receiving aromatase inhibitors for at least one month.
• Patients must complain of mild to moderate arthralgia.
• Ability to understand and sign informed consent.
• Patients meet criteria for low to moderate risk for moderate exercise based oon the ACSM guidelines.

Exclusion criteria

• Inability to comply with study requirements.
• Metastatic breast cancer.
• Patients with orthopedic or neuromuscular disorders that preclude participation in exercise.
• Rheumatoid arthritis.
• History of MI, angina or congestive heart failure.
• Pregnant or lactating females.
• Patients that are high risk for moderate exercise based on ACSM risk classification.
• Patients who exceed minimal physical activity recommendations from the US Surgeon General's Report: Accumulation of 30 minutes or more of moderate physical activity on most days of the week.
• Morbidly obese with BMI ≥ 40

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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27 participants in 1 patient group

Exercise

Experimental group

Description:

Subjects will be participating in a home-based flexibility and exercise program

Treatment:

Behavioral: Exercising block