Exercise Program for Arteriovenous Fistula Maturation (FAVULOUS)

Civil Hospices of Lyon

Status: Enrolling

Conditions: Arteriovenous Fistula

Treatments: Procedure: Handgrip exercise program

Study type: Interventional

Funder types: Other

Identifiers

NCT04034433

ID-RCB (Other Identifier)

69HCL19_0215

Details and patient eligibility

About

Arteriovenous fistula (AVF) is the recommended vascular access for chronic hemodialysis, as it is associated with less mortality and better patency than arteriovenous graft (AVG) or central venous catheter (CVC).

Unfortunately, AVF suffers from a high failure rate, due, in part, to poor venous diameter.

The aim of this study is to investigate whether a perioperative handgrip training can improve the diameter of AVF in patients with chronic kidney disease (CKD) (stage IV-V).

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients older than 18 years
• with chronic kidney disease (Estimated Glomerular Filtration Rate (eGFR) <30 milliLiter/minute (mL/min))
• with follow-up at the University Hospital of Lyon Sud
• who choose hemodialysis as renal replacement therapy

Exclusion criteria

• contraindication for arteriovenous fistula (AVF) surgery
• refusing AVF creation
• prior vascular access
• antecedent of IV substance abuse
• active cancer
• inability to perform handgrip exercise
• physical or mental disability limiting follow-up possibility
• inclusion in an other interventional study
• no social welfare

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

Exercise

Experimental group

Treatment:

Procedure: Handgrip exercise program

Control

No Intervention group