Exercise Study in Patient With Chronic Obstructive Pulmonary Disease (0000-036)

Merck Sharp & Dohme (MSD)

Status and phase: Terminated; Phase 2

Conditions: Chronic Obstructive Pulmonary Disease (COPD)

Treatments: Drug: Fluticasone; Drug: Comparator: Placebo

Study type: Interventional

Funder types: Industry

Identifiers

NCT00387036

2006_039

036

0000-036

Details and patient eligibility

About

To test the effect of the research study drug, inhaled fluticasone on lung function in exercising patients with Chronic Obstructive Pulmonary Disease (COPD).

Enrollment: 12 patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 40 years and older
• Clinical diagnosis of COPD for greater than one year
• History of cigarette smoking

Exclusion criteria

• Other lung diseases (not including COPD), such as asthma
• A condition that could interfere with your ability to perform exercise tests

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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12 participants in 2 patient groups

1

Other group

Description:

Arm 1: drug, crossing over to Pbo comparator

Treatment:

Drug: Fluticasone

2

Other group

Description:

Arm 2: Pbo comparator, crossing over to drug

Treatment:

Drug: Fluticasone

Drug: Comparator: Placebo