Exercise Therapy in Cancer Patients Who Are Recovering From COVID-19

Memorial Sloan Kettering Cancer Center (MSK)

Status and phase: Completed; Phase 1

Conditions: Covid19; Cancer; Coronavirus

Treatments: Other: Aerobic Exercise Therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT04824443

21-101

Details and patient eligibility

About

The purpose of the study is to evaluate the safety and tolerability of a 30-week aerobic exercise therapy program in cancer patients recovering from COVID-19. The study will look at whether the aerobic exercise therapy causes few or mild side effects in participants. Aerobic exercise is physical activity that uses the large muscle groups (muscles in your legs, buttocks, back, and chest) and can be performed for several minutes at a time. The aerobic exercise therapy being used in this study will be a walking program that will be adjusted so it matches participant fitness levels (how much exercise you can handle).

Enrollment: 3 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18

• Previously admitted to a hospital for Covid-19

• Discharged from hospital for at least 30 days

• Previously treated for cancer at MSK

• Interval of ≥ 12 months but ≤ 10 years following completion of primary non-hormonal anti-cancer therapy (current endocrine therapy and maintenance therapy allowed)

• Space to house a treadmill at personal residence

• Cleared for exercise participation as per screening clearance via the Physical Activity Readiness Questionnaire (PAR-Q+)

• Performing less than 90 minutes of structured moderate-intensity or strenuous-intensity exercise per week, as evaluation by self-report

• If a female of child-bearing potential, must not be pregnant or planning to become pregnant during the study.

  • Women <50 years old who are of child-bearing potential must have a negative pregnancy test within 14 days of enrollment.

Exclusion criteria

• Currently receiving home oxygen after discharge
• Enrollment onto any other interventional investigational study
• Current treatment for any other diagnosis of invasive cancer of any kind
• Distant metastatic malignancy of any kind
• Receiving non-hormonal anticancer therapy
• Any other condition or intercurrent illness that, in the opinion of the investigator, makes the subject a poor candidate for study participation

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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3 participants in 1 patient group

Participants who were hospitalized for COVID-19

Experimental group

Description:

Participants will be post-cancer treatment patients who were hospitalized for COVID-19.

Treatment:

Other: Aerobic Exercise Therapy