Exercise Training Effect in Patients With HF and PEF

MultiCare Health System Research Institute

Status: Completed

Conditions: Heart Failure

Treatments: Behavioral: Exercise Training

Study type: Interventional

Funder types: Other

Identifiers

NCT02696486

15.20

Details and patient eligibility

About

The purpose of this is to develop and implement a pilot study that will demonstrate the ability to recruit, enroll, retain, conduct exercise training, and collect pre and post outcomes on the effect of exercise training on quality of life (QOL) and exercise capacity in patients with a diagnosis of heart failure with preserved ejection fraction (HFPEF).

Enrollment: 16 patients

Sex: All

Ages: 55+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 55 years (Interested in capturing mean ages close to age 65 as many HF initiatives are based on this age group and HF development increases with aging).
• Diagnosis of HFPEF stable NYHA Stage II- III with an EF of ≥ 45%
• Stabilized on cardiac medications and post hospitalization > 4 weeks
• Ability to participate in exercise testing and training.
• Referral from Cardiologist or primary care physician.

Exclusion criteria

• Unstable Angina
• Uncontrolled diabetes
• Moderate to severe aortic stenosis
• Uncontrolled hypertension Systolic BP>150 mm Hg or Diastolic BP >100 mm Hg
• Valvular heart disease
• Untreated coronary artery stenosis >50%
• Arrhythmias
• Pulmonary disease/COPD
• Dementia or cognitive impairment
• VAD or Transplant planned in next 6 months.
• Current or recent participation in a Cardiac Rehab program within the last six months.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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16 participants in 1 patient group

Exercise Training

Experimental group

Treatment:

Behavioral: Exercise Training