Exercise Training in Individuals With Coronary Artery Disease (ReKoBo)

University Medical Centre Ljubljana

Status: Completed

Conditions: Coronary Artery Disease; Myocardial Infarction

Treatments: Other: Exercise training

Study type: Interventional

Funder types: Other

Identifiers

NCT03821558

UKCLRehab0012019

Details and patient eligibility

About

In this controlled trial, patients referred to post-myocardial infarction cardiac rehabilitation will be randomized to either interval or continuous training.

Full description

The trial would i) compare the acute effects of each exercise type on selected cardiovascular indicators; ii) compare the chronic effects of each exercise type on selected cardiovascular indicators; iii) provide information on the association between acute and chronic effects of each exercise type; iv) provide insight into possible mechanisms of effectiveness of each exercise type; v) identify the most safe and effective exercise type for patients with coronary artery disease.

Enrollment: 115 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• myocardium infarction 120 days prior to cardiac rehabilitation

Exclusion criteria

• contraindications for exercise training,
• uncontrolled dysrhythmias,
• uncontrolled heart failure (New York Heart Association (NYHA) stage IV),
• intellectual development disorder,
• pregnancy.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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115 participants in 2 patient groups

Interval training group

Active Comparator group

Description:

Patients to be randomized to the 'interval training group' will have exercise training sessions 3 times per week for a period of 12 weeks. During training, they will undergo interval exercise series composed of high-intensity intervals (80-90% of peak exercise performance) and low-intensity intervals (60-70% of peak exercise performance).

Treatment:

Other: Exercise training

Continuous training group

Active Comparator group

Description:

Patients to be randomized to the 'continuous training group' will have exercise training sessions 3 times per week for a period of 12 weeks. During training, they will undergo moderate continuous exercise training at 75% of peak exercise performance.

Treatment:

Other: Exercise training