EXerCise wEight Loss (EXCEL)

University of Glasgow

Status: Completed

Conditions: Overweight and Obesity

Treatments: Behavioral: Resistance exercise training + weight loss group; Behavioral: Weight loss only group (WL)

Study type: Interventional

Funder types: Other

Identifiers

NCT05702840

EXerCise wEight Loss Study

Details and patient eligibility

About

The overall aim of this study is to investigate the effects of home-based resistance exercise programme on changes in body composition and strength during weight loss, in people living with obesity or overweight.

Enrollment: 48 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Obesity or overweight (BMI ≥ 25kg/m2).
• Passing the Physical Activity Readiness Questionnaire (PAR-q+)

Exclusion criteria

• Currently take part in more than 1.5 hours of structured exercise per week.
• Having recently (<6 months) taken part in any resistance exercise training, taking any medications known to affect weight loss.
• Actively engaged in a weight loss programme, having lost more than 2kg weight in the last 6 months.
• Any other reason which would limit ability to perform the exercises and outcome measurements safely.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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48 participants in 2 patient groups

Resistance exercise training + weight loss group (RT+WL)

Experimental group

Description:

Participants (WL-RT) will be provided with a resistance exercise booklet containing instructions for exercises and links to demonstration videos. A demonstration and explanation of the exercises will be given at the beginning of the intervention, alongside a discussion of the principles of the programme such as starting level and progression. We will ask participants to perform the resistance exercises for 12-week period. Participants will be asked to perform exercises 3 times a week (3 sets reaching the RPE scale between 8 - 10 out of 10 (4-6 out of 10 in the first week)) for the intervention period. The exercises will include press-ups, band lateral raises, band seated low row, squat, lunge and calf raise.

Treatment:

Behavioral: Resistance exercise training + weight loss group

Weight loss only group (WL)

Experimental group

Description:

All participants (WL and WL-RT) will be provided with vouchers to access the weight watchers weight loss programme for a 12-week period. Weight Watchers is a commercially available programme and participants will set an initial goal to lose 5kg of body mass. If 5kg weight loss is achieved then the participant can chose further weight loss goals, as long as it would result in a body mass in the weight watchers healthy weight range (https://www.weightwatchers.com/uk/weight-loss/programme/tools/healthy-weight-chart).This plan works on the basis of an individualised points plan that can then be used by the participant to select foods/meals to consume throughout the day.

Treatment:

Behavioral: Weight loss only group (WL)