Exercise With Blood Flow Restriction in Knee Osteoarthritis (BFROA)

University of Valencia

Status: Completed

Conditions: Knee Osteoarthritis

Treatments: Other: BFR resistance exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT05274932

OA-22-01

Details and patient eligibility

About

The purpose of this study is to evaluate the neuromuscular responses, pain intensity and rate of perceived exertion in patients with severe knee osteoarthritis in a preoperative setting with low-load resistance training with blood flow restriction at different levels of arterial occlusion pressure.

Enrollment: 22 patients

Sex: All

Ages: 55+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• men and women above 55 years old.
• diagnosed with severe knee osteoarthritis.
• scheduled for unilateral TKA surgery in a local hospital during 2021- 2022.

Exclusion criteria

• pain in the contralateral limb (maximum pain, ≥80 of 100 mm on a VAS during daily activities).
• another hip or knee joint replacement in the previous year.
• any medical condition in which exercise was contraindicated.
• participated in exercise programs (>2 days/week, training at intensities of 10-15RM) in the 6 months prior to the study.
• history of stroke, brain surgery, major depression, or any self-perceived cognitive alterations that could affect the performance of dual tasks.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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22 participants in 3 patient groups

Placebo

Active Comparator group

Description:

Knee extensions with 30% 1RM and no occlusion pressure.

Treatment:

Other: BFR resistance exercise

BFR at 40% AOP

Experimental group

Description:

Knee extensions with 30% 1RM and BFR at 40% AOP.

Treatment:

Other: BFR resistance exercise

BFR at 80% AOP

Experimental group

Description:

Knee extensions with 30% 1RM and BFR at 80% AOP.

Treatment:

Other: BFR resistance exercise