Exercise,Metabolic Syndrome and Weight Regain (Echocardiography Substudy)

University of Missouri (MU)

Status: Completed

Conditions: Obesity; Metabolic Syndrome

Treatments: Procedure: Stress Echocardiography

Study type: Interventional

Funder types: Other

Identifiers

NCT00543985

R01DK067036 (U.S. NIH Grant/Contract)

R01DK067036 (Echo substudy)

Details and patient eligibility

About

We plan to test the hypothesis that patients with metabolic syndrome will have impaired left ventricular diastolic parameters. These parameters will be measured before and after a stress test at the end of a 3 month period of exercise training and a 10% weight loss.

Full description

Patients must have 2 of the 5 criteria for metabolic syndrome and be able to exercise in a monitored setting for 45 min 5 times a week.

Enrollment: 36 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 2 of 5 criteria for metabolic syndrome
• Ability to exercise for 45 min 5 days a week

Exclusion criteria

• No diabetes
• Established coronary disease

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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36 participants in 1 patient group

Stress Echocardiography

Experimental group

Description:

Echocardiography was performed prior to and within 60 seconds of completing the standard Bruce treadmill protocol.

Treatment:

Procedure: Stress Echocardiography