Exogenous Oxidation of Fructose-glucose Mixtures During Running

University of Bath

Status: Completed

Conditions: Exercise

Treatments: Dietary Supplement: Glucose-maltodextrin; Dietary Supplement: Fructose-maltodextrin hydrogel; Dietary Supplement: Fructose-maltodextrin

Study type: Interventional

Funder types: Other

Identifiers

NCT03731065

MSES 17/18-001

Details and patient eligibility

About

The aim of this study is to characterise exogenous carbohydrate oxidation rates during exercise, when ingesting glucose (polymers) only, compared to glucose-fructose mixtures, and glucose-fructose mixtures ingested in hydrogel form.

Enrollment: 9 patients

Sex: Male

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Maximal oxygen consumption > 50 ml.kg-1.min-1
• > 1 year training in endurance running or triathlon
• No current injury or injury within the last three months
• No history of cardiac or metabolic disease such as coronary heart disease or diabetes
• No current or history of gastrointestinal issues
• Successful completion of the physical activity readiness questionnaire (PAR-Q)

Exclusion criteria

• Female
• Untrained in endurance running
• Current injury or injury within the past three months
• History of cardiac or metabolic disease such as coronary heart disease or diabetes
• History of or current gastrointestinal issues such as irritable bowel syndrome
• Unable to replicate diet and training for 3 and 5 days respectively prior to each experimental visit.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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9 participants in 3 patient groups

Fructose-maltodextrin ingestion

Active Comparator group

Description:

Ingestion of fructose and maltodextrin (glucose polymers) at a rate of 90 g carbohydrate per hour during two hours of treadmill running at 60%VO2peak.

Treatment:

Dietary Supplement: Fructose-maltodextrin

Fructose-maltodextrin hydrogel ingestion

Experimental group

Description:

Ingestion of fructose and maltodextrin (glucose polymers) encapsulated in alginate-pectin hydrogel, drinks at a rate of 90 g carbohydrate per hour during two hours of treadmill running at 60%VO2peak.

Treatment:

Dietary Supplement: Fructose-maltodextrin hydrogel

Glucose-maltodextrin ingestion

Active Comparator group

Description:

Ingestion of glucose and maltodextrin (glucose polymers) at a rate of 90 g carbohydrate per hour during two hours of treadmill running at 60%VO2peak.

Treatment:

Dietary Supplement: Glucose-maltodextrin