Experience of the Patient Treated With Trastuzumab (Herceptin ®) as Adjuvant for Breast Cancer (HER-ception)

Centre Francois Baclesse

Status

Completed

Conditions

Breast Cancer

Treatments

Other: questionnaires

Study type

Interventional

Funder types

Other

Identifiers

NCT01400438

HER-ception

Details and patient eligibility

About

Many studies have been devoted to the quality of life of patients during adjuvant chemotherapy for breast cancer by highlighting fatigue, psychological distress and impact on the immediate environment (spouse, children) during this difficult time for women. Curiously, no study to date has been submitted or published about how women with a one-year treatment "extra" Herceptin ® live this period in terms of quality of life, in terms of psychological impact for themselves and their families.

The investigators have no more data on how often they return to work during this treatment or on the psycho-social parameters which underpin them. It therefore seemed interesting to "give a spotlight" on this particular period in these women HER2 + by comparing a patient population of same age receiving the same adjuvant but with no Herceptin ®.

Enrollment

70 patients

Sex

Female

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Women aged over 18
Invasive breast carcinoma confirmed histologically
Non-metastatic cancer
Surgery of the primary tumor performed (mastectomy or lumpectomy) and associated with an audit axillary (sentinel node and / or axillary dissection)
Patient should receive their last course of adjuvant chemotherapy (3 FEC and 3 Taxotere)
Patients not receiving the third course of Taxotere because of toxicities may be included in the fifth course of chemotherapy is the second of Taxotere
For the group Herceptin ®: HER2 overexpression without contraindication to treatment administration
For the control group: no indication for Herceptin ®
Radiation therapy and / or adjuvant hormonal therapy allowed
Free and informed consent signed

Exclusion criteria

Women under 18 or over 60 years
Histology other than adenocarcinoma
Metastatic Breast Cancer
Chemotherapy neoadjuvant
Surgery of the primary tumor unrealized
Lack of adjuvant chemotherapy with Taxotere 3 FEC and 3
Patients with a history of malignancy within 5 years, outside of a basal cell cancer or cancer of the cervix treated and cured
Patient under guardianship or unable to give informed consent,
Pregnant or lactating
Patient unable to undergo a medical for geographical, social or psychopathological