Explanted Lung Tissues With Pulmonary Fibrosis

The University of Chicago

Status: Enrolling

Conditions: Pulmonary Fibrosis

Study type: Observational

Funder types: Other

Identifiers

NCT00515567

14514A

Details and patient eligibility

About

The goal of this study is to use the tissues from the explanted lungs in order to better study the cause of pulmonary fibrosis at a cellular level.

Full description

Pulmonary Fibrosis involves scarring of the lung. Gradually, the air sacs of the lungs become replaced by fibrotic tissue. The most current thinking is that the fibrotic process is a reaction to tiny injury to the lung. When the scar forms, the tissue becomes thicker causing a permanent loss of the tissue's ability to carry oxygen into the bloodstream.

We need to obtain lung tissue from patients without pulmonary fibrosis and compare it to lung tissue from patients with pulmonary fibrosis.

Enrollment: 90 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• all patients awaiting lung transplant

Exclusion criteria

• all who will not give consent