Explicit Assessment of Thromboembolic Risk and Prophylaxis for Medical Patients in Switzerland

University Hospitals (UH)

Status: Completed

Conditions: Venous Thromboembolism

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT01277536

ESTIMATE

Details and patient eligibility

About

Until now, no risk assessment model informing about the need of thromboprophylaxis in patients admitted for an acute medical event has been validated.

The goal of this project is to indirectly validate a model developed in Geneva by a non -interventional study involving the collection of patient characteristics during the hospitalization and a 3-month follow-up. These data will allow for the determination of the patient's risk, according to the Geneva model, and its validity, according the actual thrombo-embolic events, corrected for the thromboprophylaxis received.

The project is multicentric in Switzerland (5-10 centers) and should involve about 1000 patients.

First amendment (may 2011) : we have obtained the IRB approval for collecting data from patients who die during their hospital stay and for whom informed consent is not be possible to obtain.

Enrollment: 1,478 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients admitted (minimal stay >24 hours) to medical hospital wards
• Age ≥18 years
• Ability to give an informed consent, as informed by the physicians in charge of the patient

Exclusion criteria

• Patients admitted to non-medical hospital wards
• Patients with therapeutic anticoagulation at hospital admission
• Patients admitted for a disease requiring therapeutic anticoagulation (MTE or other)
• Patients unable to give an informed consent, as informed by the physicians in charge of the patient
• Patients without signed informed consent
• Patients already included in this study

Trial design

1,478 participants in 1 patient group

hospitalization >24 hours