Exploration of Ejaculation Changing Mechanism After Surgery for Benign Prostatic Hyperplasia (EMMECH)

University of Limoges (UL)

Status: Terminated

Conditions: Benign Prostatic Hyperplasia; Prostate; Ejaculation

Treatments: Procedure: Search retrograde ejaculation

Study type: Interventional

Funder types: Other

Identifiers

NCT02918227

I15028 (EMMECH)

Details and patient eligibility

About

Every year in France, more than 60 000 people are operated for benign prostatic hyperplasia (BPH). This surgery is accompanied by a change or even a loss of ejaculations externalized what constitutes the main constraint for patients. Empirically, the investigators talk to the patient "retrograde ejaculation" to explain a possible loss of ejaculation. Yet the underlying mechanism of this modification or loss of ejaculation remains completely unknown. Yet the underlying mechanism of this modification or loss of ejaculation remains completely unknown. No study could not determine whether the predominant mechanism was a real retrograde ejaculation or aspermia. Moreover, technical changes are sometimes tempted to preserve antegrade ejaculation but no scientific rationale can not validate.

Full description

Every year in France, more than 60 000 people are operated for benign prostatic hyperplasia (BPH). This surgery is accompanied by a change or even a loss of ejaculations externalized what constitutes the main constraint for patients. Empirically, the investigators talk to the patient "retrograde ejaculation" to explain a possible loss of ejaculation. Yet the underlying mechanism of this modification or loss of ejaculation remains completely unknown. No study could not determine whether the predominant mechanism was a real retrograde ejaculation or aspermia. Moreover, technical changes are sometimes tempted to preserve antegrade ejaculation but no scientific rationale can not validate.

Enrollment: 12 patients

Sex: Male

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Man, at least 18 years, which is scheduled for a BPH surgery
• Sexually active
• Measurement of Residual postvoid less than 6 months
• Patients accepting the constraints of the study
• Signed Consent
• Affiliate or beneficiary of social security system.

Exclusion criteria

• Patients unable to understand the study or to give consent
• Patients with known infertility
• Patients previously operated prostate
• Patients previously treated with a natural prostate treatment (radiotherapy, microwave, radio frequency, ultrasound)
• Patients with known urethral stenosis before surgery
• Patient with impaired preoperative in ejaculation
• Patient under guardianship or under judicial protection
• Patient subject to psychiatric care

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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12 participants in 1 patient group

Search retrograde ejaculation

Experimental group

Description:

Sperm count (spz) after orgasm achieved by masturbation will be measured, corresponding to the sum of spz collected in the ejaculate (E) and the first urine after orgasm (U). These measures will be made before surgery (E1 and U1) and after surgery (E2 and U2). The values E1, E2, U1 and U2 will be achieved by multiplying the concentration of spz per unit volume by the total volume of collection.

Treatment:

Procedure: Search retrograde ejaculation