Exploratory Study of Cellular Reservoirs in Blood From HIV Infected Patients (EURECA)

Centre Hospitalier Universitaire de Besancon

Status: Completed

Conditions: HIV Infection

Treatments: Other: additional blood sample

Study type: Interventional

Funder types: Other

Identifiers

NCT02858414

P/2014/223

Details and patient eligibility

About

This study evaluates the impact of highly active antiretroviral therapy on the size of the latent viral reservoirs in resting CD4+ T cells and monocytes in HIV positive patients. The activation state of the cells will be assessed, by measuring the activation of Akt, to determine its influence on the size of the viral reservoirs.

Enrollment: 41 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• HIV infected patients under Highly Active Anti-Retroviral Therapy (HAART) or Naïve from treatment

Exclusion criteria

• Age limits
• Pregnancy
• Legal restrictions to consent

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

41 participants in 1 patient group

blood sample

Experimental group

Treatment:

Other: additional blood sample