Exploratory Study of Volatile Organic Compounds in Alveolar Breath (VOCs)

Mebo Research

Status: Completed

Conditions: Nutritional and Metabolic Diseases

Treatments: Other: Breath test

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT03451994

20111001005MEBO

Details and patient eligibility

About

The purpose of this secondary analysis is to identify breath signatures associated with idiopathic malodor conditions.

Full description

Individuals with metabolic disorders may sporadically produce malodors despite good hygiene. Analysis of volatile organic compounds (VOCs) helps to gain insights into medical conditions arising due to metabolic dysfunction as different metabolic pathways emit and or consume various VOCs. These VOCs can be detected via the exhaled breath collected and analyzed with a portable breath collection apparatus. VOC profiles will be compared with self-reported symptoms and other observations of participating subjects.

Enrollment: 23 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• good general health
• willing and able to travel to one of the participating sites

Exclusion criteria

• medical conditions that, in the opinion of the investigator, would prevent participation
• elect not to participate in the study

Trial design

23 participants in 2 patient groups

Body odor

Description:

individuals self-reporting idiopathic body odor with or without bad breath

Treatment:

Other: Breath test

Breath odor

Description:

individuals self-reporting idiopathic bad breath but no body odor

Treatment:

Other: Breath test