Exploring 8-iso Prostaglandin F2α and Adenosine Deaminase Levels in Periodontal Health and Disease

Eda Cetin Ozdemir

Status: Completed

Conditions: Periodontal Diseases

Treatments: Diagnostic Test: 8-iso Prostaglandin F2α and Adenosine Deaminase

Study type: Interventional

Funder types: Other

Identifiers

NCT06236555

2023/15, 07

Details and patient eligibility

About

This study aims to assess the diagnostic potential of gingival crevicular fluid (GCF) biomarkers, specifically 8-iso Prostaglandin F2α (8-iso-PGF2α) and adenosine deaminase (ADA), in evaluating periodontal health and disease conditions.

Full description

Conducted as a single-blind, cross-sectional investigation, this study comprised 26 individuals categorized as periodontally healthy, 27 with gingivitis, and 27 diagnosed with periodontitis. The participant pool included individuals with various periodontal concerns who were referred to the Department of Periodontology Clinic at Kahramanmaraş Sütçü İmam University. The classification of periodontal health, gingivitis, and chronic periodontitis adhered to the 2018 criteria outlined by the European Federation of Periodontology

Enrollment: 80 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients having more than 20 teeth, minimum age 18, maximum age 65

Exclusion criteria

• Patients with systemic disease, Active smokers, Pregnant women, individuals with a history of orthodontic treatment, or those who had undergone periodontal treatment, regardless of whether it was surgical or non-surgical (within the last one year),

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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80 participants in 1 patient group

Kahramanmaraş Sütçü İmam University

Other group

Description:

Patients who apply to our clinic for routine periodontal treatment will be included in the study.

Treatment:

Diagnostic Test: 8-iso Prostaglandin F2α and Adenosine Deaminase