Exploring Biological Linkage Between Circadian Disruption and Cancer Progression

Seoul National University

Status: Completed

Conditions: Breast Neoplasms

Study type: Observational

Funder types: Other

Identifiers

NCT02011815

BreastCA_circa_mech

Details and patient eligibility

About

The purpose of this study is to explore the possible association between the circadian disruption and cancer progression.

Full description

The biological markers that are assumed to bridge this association are measured and analyzed.

Enrollment: 236 estimated patients

Sex: Female

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age: 18-70
• Breast cancer patients who are getting chemotherapy for the first time in life
• Patients are either having stage 4 cancer or starting neoadjuvant chemotherapy.
• Patient have signed on the informed consent, and well understood the objective and procedure of this study

Exclusion criteria

• Patients already have received chemotherapy
• Patient had another cancer (except thyroid cancer) within 5 years
• Patient with severe medical condition
• Patient had taken psychiatric medication more than 1 month in life
• Patient worked the night shift for more than 1 month in 6 months

Trial design

236 participants in 1 patient group

Breast cancer

Description:

Diagnosed breast cancer patients who are getting chemotherapy for the first time.