Exploring Nitrous Oxide Effects for Post Traumatic Stress Disorder (PTSD) (tN2O)

Stanford University

Status and phase: Completed; Phase 2

Conditions: Post Traumatic Stress Disorder

Treatments: Drug: Nitrous Oxide

Study type: Interventional

Funder types: Other

Identifiers

NCT03375294

41822

Details and patient eligibility

About

The purpose of this study is to understand nitrous oxide effects in post traumatic stress disorder (PTSD)

Full description

Post traumatic stress disorder (PTSD) is a disabling mental health disorder that impacts the lives of individuals. This study aims to understand nitrous oxide's effects in PTSD.

Enrollment: 3 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age 18-80
• Veterans of the United States Uniformed Services
• primary diagnosis of PTSD
• sufficient severity of PTSD symptoms
• fluency in English
• capacity to provide informed consent

Exclusion criteria

• psychiatric or medical conditions that make participation unsafe
• pregnant or nursing females
• allergy to nitrous oxide

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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3 participants in 1 patient group

Nitrous Oxide

Experimental group

Description:

PTSD patients in this arm will receive a single inhalation dose of 50% nitrous oxide and 50% oxygen for 1 hour

Treatment:

Drug: Nitrous Oxide