Exploring the Application of 3D Bioprinting for Personalized Treatment in Pancreatic Ductal Adenocarcinoma

Chinese Academy of Medical Sciences & Peking Union Medical College

Status: Enrolling

Conditions: Pancreatic Ductal Adenocarcinoma

Study type: Observational

Funder types: Other

Identifiers

NCT05955092

PDAC3DP001

Details and patient eligibility

About

The goal of this observational study is to test the application value of 3D bioprinting technology in personalized treatment of pancreatic cancer.

The main questions it aims to answer are:

• Can 3D bioprinting technology be successfully applied to establish preclinical models of pancreatic cancer?
• Can 3D bioprinted preclinical models of pancreatic cancer be applied to personalized treatment of pancreatic cancer?

Participants will have tumor tissue collected to extract primary tumor cells for the establishment of in vitro preclinical models, which will be used for drug sensitivity testing.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• More than 18 years old
• Diagnosed as colorectal cancer with or without liver metastases before
• Pathologically proven colorectal cancer after surgery

Exclusion criteria

• History of other malignancies or serious medical conditions
• Inability to provide independent informed consent