Exploring the Predictive Value of Electroencephalography Features in Perioperative Neurocognitive Disorders Following Cardiovascular Surgery

Capital Medical University

Status: Enrolling

Conditions: Cardiovascular Surgery; Perioperative Neurocognitive Disorders

Treatments: Procedure: cardiovascular surgery

Study type: Observational

Funder types: Other

Identifiers

NCT06692309

DXK2022-ke-487

Details and patient eligibility

About

To explore the predictive value of Electroencephalography features in Perioperative Neurocognitive Disorders in patients undergoing cardiovascular surgery under general anesthesia

Full description

Data was acquired on the ward using a 10-20 system with a standard 32-channel EEG cap and an EEG instrument (BP Company, Gilching, Germany). Patients were tested using cognitive assessment scales before and after surgery.

Cognitive levels were assessed 1 day before surgery and 1 week after surgery (7±2 days) using the Montreal Cognitive Assessment (MoCA) . Patients were followed up one month (30±2 days) after surgery using the Telephone version of the Montreal Cognitive Assessment Scale (T-MoCA).

Preoperative and postoperative electroencephalography brain network-related indexes (such as cluster coefficient, small world index, etc.) in patients with PND will be included in the analysis.

Enrollment: 100 estimated patients

Sex: All

Ages: 60+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Written informed consent
2. undergoing coronary artery bypass surgery or valve replacement surgery under general anaesthesia
3. ASA grade: II-IV
4. older than 60 years
5. Able to complete cognitive function tests

Exclusion criteria

1. history of severe neurological diseases and psychiatric diseases
2. history of drug abuse
3. severe hearing or vision impairment
4. preoperative delirium
5. serious adverse reactions such as cardiac arrest and cardiopulmonary resuscitation during surgery
6. patients undergoing secondary surgery in a short period
7. participation in concurrent clinical trials

Trial design

100 participants in 2 patient groups

Perioperative Neurocognitive Disorders

Description:

Postoperative delirium was assessed using the confusion assessment method or the confusion assessment method for the intensive care unit (CAM/CAM-ICU) . Cognitive levels were assessed 1 day before surgery and 1 week after surgery (7±2 days) using the Montreal Cognitive Assessment (MoCA). Patients were followed up one month (30±2 days) after surgery using the Telephone version of the Montreal Cognitive Assessment Scale (T-MoCA).

Treatment:

Procedure: cardiovascular surgery

No-Perioperative Neurocognitive Disorders

Description:

Postoperative delirium was assessed using the confusion assessment method or the confusion assessment method for the intensive care unit (CAM/CAM-ICU) . Cognitive levels were assessed 1 day before surgery and 1 week after surgery (7±2 days) using the Montreal Cognitive Assessment (MoCA). Patients were followed up one month (30±2 days) after surgery using the Telephone version of the Montreal Cognitive Assessment Scale (T-MoCA).

Treatment:

Procedure: cardiovascular surgery