Exploring the Role of Almonds in Enhancing Immune Strength

San Diego State University

Status: Completed

Conditions: Immune Health

Treatments: Other: Almond; Other: Pretzel

Study type: Interventional

Funder types: Other

Identifiers

NCT05059639

2021-06-18

Details and patient eligibility

About

The COVID-19 pandemic highlights the importance of good nutritional status for immune strength and for reducing comorbidities that increase morbidity and mortality of infections. The major aim of this study is test if almond consumption can improve immune function.

Full description

Investigators will conduct an 8-week parallel-arm trial of 48 overweight/non-obese (BMI=24-30) adult (aged 40-65 years) men (n=24) and women (n=24) who will be randomly assigned to consume daily isoenergetic portions of almonds or a common snack (pretzels).

Enrollment: 48 patients

Sex: All

Ages: 40 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Healthy male and female subjects aged 40-65 y
• Body mass index (BMI) 24-30 kg/m.2

Exclusion criteria

• Not willing to stop taking multivitamins, and supplements (with the exception of vitamin D and calcium), for 30 days prior to or during study participation, if currently taking these.
• Almond allergies
• Alcohol consumption >2 drinks per day.
• Smoking or using nicotine containing products in the last 6 months.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

48 participants in 2 patient groups

Almond (2 ounces)

Experimental group

Description:

Consume 2 ounces almond daily for 8 weeks

Treatment:

Other: Almond

Pretzel

Active Comparator group

Description:

Consume comparative amount of pretzel for 8 weeks

Treatment:

Other: Pretzel