Exploring Two Treatments for Misophonia

Duke University

Status: Completed

Conditions: Misophonia

Treatments: Behavioral: Unified Protocol for Transdiagnostic Treatment of Emotional Disorders; Behavioral: Process-based Cognitive Behavioral Therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT04198597

Pro00103962

Details and patient eligibility

About

While the investigators continue to work on better understanding Misophonia, it is also important to identify treatments that can help people who are currently suffering. Further, it is important that the treatments provided are acceptable to the people who receive them. In this study, participants will complete one of two treatments the investigators believe can help manage symptoms of Misophonia: The Unified Protocol or process-based therapy. Both treatments will use evidence-based psychological principles (e.g., managing attention or behavior) in a flexible manner and will focus on developing skills to help reduce the distress and impairment associated with Misophonia. The aims of this study are (1) to explore the acceptability and feasibility of these treatments for individuals who experience Misophonia and (2) to examine whether these treatments help reduce symptoms associated with Misophonia.

Enrollment: 12 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Over age 18
• Able to read English
• Meet criteria for interfering symptoms of misophonia
• Live in North Carolina

Exclusion criteria

• Under age 18
• Current mania
• Current psychotic disorder
• Current anorexia
• Presents with a condition that requires immediate prioritization in treatment (e.g., suicide planning or intent)
• Has received any treatment specifically for misophonia in the past year

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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12 participants in 4 patient groups

Unified Protocol, 2 week baseline

Experimental group

Description:

Participants in this arm will complete two weeks of baseline assessment (during which they will complete questionnaires but not start treatment) and then receive 16 sessions of the Unified Protocol (UP). The UP is an emotion-focused treatment designed to teach participants skills to help manage difficult experiences.

Treatment:

Behavioral: Unified Protocol for Transdiagnostic Treatment of Emotional Disorders

Unified Protocol, 4 week baseline

Experimental group

Description:

Participants in this arm will complete four weeks of baseline assessment (during which they will complete questionnaires but not start treatment) and then receive 16 sessions of the Unified Protocol (UP). The UP is an emotion-focused treatment designed to teach participants skills to help manage difficult experiences.

Treatment:

Behavioral: Unified Protocol for Transdiagnostic Treatment of Emotional Disorders

Process-based treatment, 2 week baseline

Experimental group

Description:

Participants in this arm will complete two weeks of baseline assessment (during which they will complete questionnaires but not start treatment) and then receive 16 sessions of the process-based therapy. Process-based therapy is a flexible therapy designed to teach skills that help people manage difficult experiences. Patient and therapist work together to determine which skills will be utilized.

Treatment:

Behavioral: Process-based Cognitive Behavioral Therapy

Process-based treatment, 4 week baseline

Experimental group

Description:

Participants in this arm will complete four weeks of baseline assessment (during which they will complete questionnaires but not start treatment) and then receive 16 sessions of the process-based therapy. Process-based therapy is a flexible therapy designed to teach skills that help people manage difficult experiences. Patient and therapist work together to determine which skills will be utilized.

Treatment:

Behavioral: Process-based Cognitive Behavioral Therapy