Exposed Hypersensitive Dentin Treated with Fluoride Iontophoresis with Remineralizing Agents

Al-Azhar University

Status: Invitation-only

Conditions: Dentin Hypersensitivity

Treatments: Drug: Remineralization with sodium fluoride varnish; Drug: Fluoride Iontophoresis with Acidulated Phosphate Fluoride

Study type: Interventional

Funder types: Other

Identifiers

NCT06837779

FDAZUC-REC1009/2074

Details and patient eligibility

About

The goal of this clinical trial is to learn if the application of fluoride works to treat patients suffering from dentin hypersensitivity. It will also learn about the safety of using fluoride iontophoresis with Acidulated phosphate fluoride gel.

The main questions it aims to answer are:

Does the remineralizing agent have the ability to decrease dentin sensitivity?

Researchers will compare Fluoride Iontophoresis with Acidulated Phosphate Fluoride gel , Casein phosphopeptides-Amorphus calcium phosphate (CPP-ACP), nano-hydroxyapptite (NHAP) and -active glass in decreasing dentin hypersensitivity

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Participants will:

• Application of remineralizing agent every 3 months
• Visit the dental clinic once every 3 months for checkups and tests

Full description

Assess the efficacy of fluoride iontophoresis in remineralization in comparison with other ingredients.

Enrollment: 20 estimated patients

Sex: All

Ages: 35 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients within 35-60 years of age.
• Each patient has 4 or more exposed roots of posterior teeth having sensitivity.
• Good oral hygiene.
• Patients who will agree to the consent and will commit to the follow-up period.
• Patients will follow instructions during study time.
• Teeth that were vital.

Exclusion criteria

• Patients with any systemic disease that may affect normal healing.
• Patient with bad oral hygiene, high caries index and high plaque index
• Patients participating in more than 1 dental study.
• Active carious lesions.
• Intrinsic and extrinsic stains.
• Any previous filling of selected teeth.
• Cracked and malformed teeth.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Triple Blind

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20 participants in 2 patient groups

Fluoride Iontophoresis with Acidulated Phosphate Fluoride gel

Experimental group

Description:

assessmen of iontophoresis effect on flouride ions flush to remineralization of demineralized enamel .The treatment will be assessed and recorded using VAS score immediately after the intervention, 3 months, 6 months and one year later.

Treatment:

Drug: Fluoride Iontophoresis with Acidulated Phosphate Fluoride

remineralizing agents

Active Comparator group

Description:

All remineralizing agents (Casein phosphopeptides -Amorphus Calcium Phosphate, Nano-hydroxyapatite, and Bioactive glass).

Treatment:

Drug: Remineralization with sodium fluoride varnish