Expression of Oncogenic Human Papillomavirus E6/E7 Protein in Tampon Self-Tests

University of Aarhus

Status: Completed

Conditions: Uterine Cervical Neoplasms; Normal Uterine Cervical Cytology; Uterine Cervical Dysplasia

Study type: Observational

Funder types: Other

Identifiers

NCT00526370

TP07-2351

Details and patient eligibility

About

The purpose of this study is to examine for HPV E6/E7 mRNA in tampon self-tests, and compare with the cytological and histological diagnoses.

Study Hypothesis: Expression of HPV E6/E7 mRNA in Tampon self-tests are a suitable alternative to the routine cervical smear.

Enrollment: 72 patients

Sex: Female

Ages: 23+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Women with cervical dysplasia been referred to conisation.
• Women invited to cervical screening program and with only normal smear and normal smears in their history.

Exclusion criteria

• Women not performing the tampon self-test before conisation.
• Women not performing the tampon self-test at least 3 month after having a normal PAP-smear taken.

Trial design

72 participants in 2 patient groups

A

Description:

Women with at least moderate dysplasia in biopsies from cervix uteri

B

Description:

Women with only normal PAP-smears