Expression of PARP-1 in Multiple Sclerosis Patients

Sohag University

Status: Completed

Conditions: Multiple Sclerosis

Treatments: Genetic: Blood sampling

Study type: Interventional

Funder types: Other

Identifiers

NCT05196425

Soh-Med-21-05-12

Details and patient eligibility

About

This study will explore the expression of PARP-1 in optic neuritis of multiple sclerosis patients.

The data will be collected from Sohag University hospital in the period from the start of August 2021 to the end of December 2021.

The study protocol will be approved by the Scientific Research Ethical Committee, Faculty of Medicine, Sohag University.

Enrollment: 80 patients

Sex: All

Ages: 20 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with multiple sclerosis with or without optic neuritis Multiple sclerosis will be diagnosed according to the McDonald criteria

Exclusion criteria

• • Isolated optic neuritis.

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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80 participants in 3 patient groups

Control group

Other group

Treatment:

Genetic: Blood sampling

MS with optic neuritis

Active Comparator group

Treatment:

Genetic: Blood sampling

Ms without optic neuritis

Active Comparator group

Treatment:

Genetic: Blood sampling