Extended Rhythm SCreening for AtRial Fibrillation in Cryptogenic Stroke Patients (SCARF)

Medisch Spectrum Twente

Status: Terminated

Conditions: Atrial Fibrillation; Stroke

Study type: Observational

Funder types: Other

Identifiers

NCT01550042

P11-25 (Other Identifier)

NL36491.044.11

Details and patient eligibility

About

Recent studies demonstrated that prolonged rhythm observation increases the detection of atrial fibrillation in patients prior diagnosed as cryptogenic stroke. Detection of atrial fibrillation in these patients has important therapeutic implications for the anticoagulation regimen. However, data on optimal monitoring duration and method of AF detection are limited.

Enrollment: 4 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients > 18 years of age Recent episode (≤60 days) of cryptogenic ischemic stroke
• Undetermined etiology with negative evaluation (including cardioembolism work- up) according to the criteria for the Trial of Org 10172 in Acute Stroke Treatment (TOAST)
• Implantation of an implantable loop recorder within two months after index event
• Able of providing informed consent

Exclusion criteria

• Pre-existing indication for vitamin K antagonist
• Untreated hyperthyroidism
• Indication for pacemaker implantation, implantable cardioverter defibrillator (ICD) or Cardiac Resynchronisation Therapy (CRT)
• Severe co-morbidity not likely to complete follow-up for one year

Trial design

4 participants in 1 patient group

Intensive observation cohort

Description:

Patients \> 18 years of age diagnosed with a recent episode of cryptogenic stroke with long term rhythm observation using an implantable loop recorder for detecting atrial fibrillation.