Extended Spectrum Betalactamase Producing Bacteria; Epidemiology and Treatment in Non-hospitalized Patients (ESCAPE)

Vestre Viken Hospital Trust

Status: Completed

Conditions: Environmental Contamination of ESBL; Urinary Tract Infection; Infection Due to ESBL Bacteria

Study type: Observational

Funder types: Other

Identifiers

NCT01838213

REK S-08901b

Details and patient eligibility

About

This project aims at investigating the duration of human fecal carriage of bacteria harboring plasmid-borne resistance genes expressing Extended Spectrum beta-lactamases (ESBL), risk factors for infections with such bacteria and persistence, mobility and spread of ESBL in the environment and within households. It also aims to compare different methods of detecting ESBL carriage and treat patients with urinary tract infection caused by these bacteria.

Enrollment: 760 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients >=18 of age with a urine culture yielding E. coli or K. pneumoniae >10.000 colony forming units/mL.

Exclusion criteria

• Patients who have lived in Norway for <1 year
• Patients who are unable to answer a questionaire
• Patients who have been infected with an ESBL producing bacteria before
• Patients who have been admitted to a hospital or a long term care facility for >24 hours during the past 31 days.