Extending the hCG OPU Interval (DelOPU)

Baruch Padeh Medical Center

Status: Unknown

Conditions: Infertility

Treatments: Other: Delaying oocyte pick up beyond 39 hours post hCG

Study type: Interventional

Funder types: Other

Identifiers

NCT02871154

0041-16-POR

Details and patient eligibility

About

Our and others experience suggest that in some cases delaying oocyte pick up (OPU) for more than 39 hours after hCG injection may be of benefit.

We plan to apply this to 20 women in whom less than 20% of oocytes were found suitable for intracytoplasmic sperm injection. The delay will be for up to an interval of 47 hours from hCG to OPU.

Full description

In IVF one encounters some women in whom a low percentage of oocytes are found in the metaphase II stage upon their retrieval. Following some incidents, in our experience as well as others', where women injected hCG too early but oocytes were still retrieved with high proportion of maturity, we decided to delay OPU intentionally in women who had low percentage oocyte maturity in previous cycles.

Enrollment: 20 estimated patients

Sex: Female

Ages: 20 to 38 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: Previous 2 oocyte pick up cycles with 20% metaphase II oocytes in the cohort -

Exclusion Criteria:

No previous IVF history

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

Delay

Experimental group

Description:

Delaying oocyte pick up beyond 39 hours post hCG

Treatment:

Other: Delaying oocyte pick up beyond 39 hours post hCG