External Oblique and Rectus Abdominis Plane Block Versus Quadratus Lumborum Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy

Tanta University

Status: Enrolling

Conditions: Postoperative Analgesia; Quadratus Lumborum Block; Laparoscopic Cholecystectomy; External Oblique and Rectus Abdominis Plane Block

Treatments: Other: External oblique and rectus abdominis plane block; Other: Quadratus lumborum block

Study type: Interventional

Funder types: Other

Identifiers

NCT07082387

36264PR1261/6/25

Details and patient eligibility

About

This study aims to compare the effects of the external oblique and rectus abdominis plane (EXORA) block and the quadratus lumborum block (QLB) on postoperative analgesia in patients undergoing laparoscopic cholecystectomy (LC).

Full description

Laparoscopic cholecystectomy (LC) is a proven, gold standard surgical procedure for the management of gallbladder stones.

The quadratus lumborum block (QLB) is a regional block that would appear to be similar to the posterior TAP block, although the drug injection area is deeper and more dorsal than the transverse abdominal aponeurosis.

The external oblique and rectus abdominis plane (EXORA) block is an emerging technique providing a sensory block to the anterolateral abdominal wall.

Enrollment: 80 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age from 18 to 65 years.
• Both sexes.
• American Society of Anesthesiology (ASA) physical status I-II.
• Undergoing laparoscopic cholecystectomy (LC) under general anesthesia.

Exclusion criteria

• History of allergies to local anesthetics.
• Opioid dependency.
• Bleeding or coagulation disorders.
• Psychiatric and neurological disorder.
• Local infection at the site of injection.
• Body mass index (BMI) > 35.
• Hypertension.
• Uncontrolled diabetes mellitus.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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80 participants in 2 patient groups

EXORA group

Experimental group

Description:

Patients will receive an external oblique and rectus abdominis plane (EXORA) block using 20ml of bupivacaine 0.25%.

Treatment:

Other: External oblique and rectus abdominis plane block

QLB group

Experimental group

Description:

Patients will receive a quadratus lumborum block (QLB) using 20ml of bupivacaine 0.25%.

Treatment:

Other: Quadratus lumborum block