A Multicenter External Validation of a Novel Prediction Model for Elbow Flexion Recovery After Nerve Transfer Surgery in Brachial Plexus Injuries

Siriraj Hospital

Status: Completed

Conditions: Brachial Plexus Injury

Treatments: Procedure: Nerve transfer surgery for elbow flexion

Study type: Observational

Funder types: Other

Identifiers

NCT06237270

123/2566(IRB1), LH671009

Details and patient eligibility

About

The goal of this observational study is to validate a risk prediction model developed for unsuccessful elbow flexion recovery after nerve transfer surgery in patients with brachial plexus injury. The main question it aims to answer is how well a risk prediction model perform in a different dataset, which are patients with brachial plexus injury who underwent surgery in a different time period or a different hospital.

Enrollment: 200 patients

Sex: All

Ages: 10+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Traumatic brachial plexus injury patients underwent nerve transfer operation for re-innervation of elbow flexion at Siriraj Hospital between 2018 and 2020 and Lerdsin General Hospital between 2008 and 2022
• Patients had follow-up duration at least 24 months after surgery

Exclusion criteria

• Incomplete medical records
• Patients underwent free functioning muscle transfer as primary surgery for elbow flexion
• Obstetric brachial plexus injury
• Radiation-induced brachial plexopathy

Trial design

200 participants in 2 patient groups

Successful biceps recovery

Description:

Motor power more than or equal to grade 3 at 24 months after surgery

Treatment:

Procedure: Nerve transfer surgery for elbow flexion

Failure of biceps recovery

Description:

Motor power less than grade 3 at 24 months after surgery

Treatment:

Procedure: Nerve transfer surgery for elbow flexion