Extracellular Vesicle Cargo in Obesity and Type 2 Diabetes

Mayo Clinic

Status: Completed

Conditions: Diabetes; Insulin Resistance; Glucose Intolerance

Study type: Observational

Funder types: Other

Identifiers

NCT06401876

21-003883

Details and patient eligibility

About

The purpose of this research is to obtain blood samples before and after a bariatric procedure to better understand the reasons for glucose intolerance and insulin resistance (diabetes) in the obesity, and the reasons for improvement of diabetes after bariatric surgery

Enrollment: 24 patients

Sex: All

Ages: 21+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Enrolled in the Bariatric Surgery Program.
• Patients with A1c of 6.5 or higher within the last 6 months. OR
• Patients with A1c less than 6.5; have diagnosis of stable type 2 diabetes for > 6 months.

Exclusion criteria

• Disqualified for Bariatric Surgery.
• BMI < 35 kg/m^2.