Extubation Criteria in Patients Greater Than 59 Years of Age

Wake Forest University (WFU)

Status: Completed

Conditions: Respiratory Complications; Extubation

Study type: Observational

Funder types: Other

Identifiers

NCT04596735

IRB00063713

Details and patient eligibility

About

Prospectively evaluate the predictive value of individual pre-specified clinical extubation criteria for extubation success

Full description

Perform a prospective observational study to evaluate routine criteria commonly used to extubate elderly patients in the operating room after non-cardiac and non-thoracic surgery to ultimately reduce the incidence of near-term reintubation and by extension other respiratory complications

Enrollment: 4,000 patients

Sex: All

Ages: 60+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• >= 60 years of age
• Patients undergoing general endotracheal anesthesia for surgery or invasive diagnostic procedures that are anticipated to be extubated immediately following the procedure

Exclusion criteria

• Age<60 years of age
• Patients with a tracheostomy in - situ (pre-existing or placed as part of the index procedure)
• Patients undergoing cardiac surgical procedures
• Patients undergoing general endotracheal anesthesia who are not anticipated to be extubated immediately following the surgical procedure
• Patients with delayed extubations in the post anesthesia care unit or intensive care unit)
• Patients undergoing TIVA (Total Intravenous Anaesthesia)
• Patient with an initial room air SpO2<93%
• Patients with VADS (ventricular assist device) undergoing non-cardiac surgery
• Thoracic surgical procedures
• Patients on home oxygen
• Patients getting general anesthesia with supraglottic airway

Trial design

4,000 participants in 1 patient group

Patients undergoing general endotracheal anesthesia that will be extubated following the procedure

Description:

Patients 60 years of age and older undergoing general anesthesia and non-cardiac surgery will be observed by a member of the research team independent from the team caring for the patient at the time of emergence and extubation