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Eye Movement Desensitization and Reprocessing (EMDR) to Treat Chronic Pruritus

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University Hospital Basel

Status

Not yet enrolling

Conditions

Chronic Pruritus

Treatments

Behavioral: Eye Movement Desensitization and Reprocessing

Study type

Interventional

Funder types

Other

Identifiers

NCT06771375
2024-02597, th24schaefert

Details and patient eligibility

About

Pruritus is a common symptom of numerous dermatological and non-dermatological conditions. Current treatments for chronic pruritus (CP) are often not fully effective and may have burdensome side effects. Recently, the trauma exposure technique Eye Movement Desensitization and Reprocessing (EMDR) that is recommended as first line treatment for posttraumatic stress disorder has been reported to be also effective in the treatment of CP in anecdotal clinical case observations. However, to the best of the investigator's knowledge, the efficacy of EMDR in CP has not yet been systematically explored. This study aims at addressing this unmet need in a prospective pilot study comparing EMDR versus treatment as usual (TAU).

Enrollment

30 estimated patients

Sex

All

Ages

18 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Provided written informed consent
  • Age 18 to 75 years
  • Skindex-29 (questionnaire) symptoms subscale ≥42
  • Confirmed diagnosis CP
  • Itch intensity of min. ≥ 4 on the 0-10 numerical rating scale within the last 7 days
  • Stable course of treatment in the two weeks prior to the study

Exclusion criteria

  • Inability to follow the procedures of the study, e.g. due to language problems, severe psychiatric disorders such as delusional disorder, suicidality or dementia.
  • Patients on phototherapy
  • Acute attacks of an autoimmune disease such as Crohn's disease
  • Serious cardiac disease

Trial design

Primary purpose

Treatment

Allocation

Non-Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

30 participants in 2 patient groups

Intervention Group
Experimental group
Description:
EMDR (Eye Movement Desensitization and Reprocessing)-Treatment of patients suffering from CP + Treatment as Usual (TAU).
Treatment:
Behavioral: Eye Movement Desensitization and Reprocessing
Standard of care group
No Intervention group
Description:
Treatment as Usual (TAU) - depending on the underlying disease

Trial contacts and locations

1

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Central trial contact

Chrysovalandis Schwale, Dr.; Rainer Schaefert, Prof.

Data sourced from clinicaltrials.gov

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