Eyelash Effect Evaluation for Premium Rejuvenation Eyelash Serum

Hungkuang University

Status: Active, not recruiting

Conditions: Hair Health; Skin Condition; Eyelashes; Skin Health; Eyelash Growth

Treatments: Other: Placebo control; Other: Experimental formula

Study type: Interventional

Funder types: Other

Identifiers

NCT07271199

25-089-A

Details and patient eligibility

About

This study aims to evaluate the efficacy of the Premium Rejuvenation Eyelash Serum on eyelashes and the surrounding periorbital skin. A total of 30 healthy female participants, aged 18 to 60, will be recruited and randomly assigned to two groups receiving different serum formulations. Participants will apply the product twice daily for 112 days (16 weeks), with eyelash and periorbital skin conditions assessed at multiple time points using non-invasive measurements. Key parameters include eyelash density, eyelash length, and overall periorbital skin condition. At the end of the study (Day 112), both participant self-assessments and evaluations by an eyelash specialist will be conducted to assess changes in eyelash and skin condition.

Full description

This prospective, randomized, double-blinded, placebo-controlled study aims to investigate the effects of Premium Rejuvenation Eyelash Serum on eyelashes and surrounding periorbital skin. A total of 30 healthy female adults aged 18 to 60 will be enrolled. Inclusion criteria require participants to be free from chronic diseases, major illnesses (including cancer, stroke-related disorders, paralysis, acute myocardial infarction, coronary artery bypass surgery, end-stage renal disease, or major organ/hematopoietic stem cell transplants), and allergic constitutions. Exclusion criteria include current use of medications or eyelash care products.

Participants will be randomly assigned into two groups of 15 each: Group 1 uses placebo (Base formula without active ingredient); Group 2 uses the experimental formula with ginger (Zingiber officinale)-derived extracellular vesicle + turmeric (Curcuma longa)-derived extracellular vesicles + IGF-1 + FGF-7. . Baseline assessments will be conducted prior to product use. Follow-up assessments will occur at Days 28 (4 weeks), 56 (8 weeks), 84 (12 weeks), and 112 (16 weeks). Evaluations will include eyelash density, change in eyelash length, self-reported periorbital skin condition (e.g., swelling, irritation, pigmentation, redness, and allergic reactions), and a questionnaire. Eyelash parameters will be objectively measured using the Canfield Scientific VISIA® Skin Analysis System. At the conclusion of the study (Day 112), both participant self-assessments and evaluations by an eyelash specialist will be conducted to assess eyelash and surrounding skin condition.

Enrollment: 30 patients

Sex: Female

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy female adults from the age of 18 to 60 years (inclusive).
• Having symptoms of alopecia, baldness, or self-identified with hair thinning.
• Absence of chronic diseases, major illnesses, or allergies.
• Major illnesses include cancer, post-stroke disorders, paralysis, acute myocardial infarction, coronary artery bypass surgery, end-stage renal disease, and major organ transplant or hematopoietic stem cell transplant

Exclusion criteria

• Currently taking any medication or using any eyelash care products.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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30 participants in 2 patient groups, including a placebo group

Group 1: Placebo control

Placebo Comparator group

Description:

Base formula without active ingredient

Treatment:

Other: Placebo control

Group 2: Experimental formula

Experimental group

Description:

Base formula with ginger (Zingiber officinale)-derived extracellular vesicle, turmeric (Curcuma longa)-derived extracellular vesicles, insulin growth factor-1 (IGF-1), and fibroblast growth factor-7 (FGF-7).

Treatment:

Other: Experimental formula