[F-18]Fluoro-DOPA PET Imaging of Brain Tumors in Children

Cincinnati Children's Hospital Medical Center

Status: Withdrawn

Conditions: Brain Tumors

Treatments: Drug: [F-18]Fluoro-DOPA PET, a diagnostic radiopharmaceutical

Study type: Observational

Funder types: Other

Identifiers

NCT00556153

CCHMC IRB# 04-09011

Details and patient eligibility

About

The first phase of the study will investigate if there is increased uptake of [F-18]FDOPA in pediatric brain tumors when compared to normal brain tissue.

Full description

The first phase of the study will investigate if there is increased uptake of [F-18]FDOPA in pediatric brain tumors when compared to normal brain tissue. Tne subjects between ages 5 and 17 years will be studies, to determine if there is increased uptake of [F-18]FDOPA in pediatric brain tumors when compared to normal brain tissue. Drug safety will also be monitored.

Sex: All

Ages: 5 to 15 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Documented brain tumor at diagnosis or relapse, including high grade glioma, low grade glioma, medulloblastoma including PNET, optic pathway glioma, brainstem glioma, ependymoma.

Exclusion criteria

• Pregnancy
• Requirement for sedation
• Lack of informed consent

Trial design

0 participants in 1 patient group

Phase I

Description:

Children, ages 5-15 years with brain tumors

Treatment:

Drug: [F-18]Fluoro-DOPA PET, a diagnostic radiopharmaceutical