F-BEVAR vs Open Surgery for Complex Abdominal Aortic Aneurysm

Institute of Hospitalization and Scientific Care (IRCCS)

Status: Completed

Conditions: Aneurysm Aortic; Vascular Diseases

Treatments: Procedure: Open repair; Procedure: Fenestrated and branched endovascular aortic repair (F-BEVAR)

Study type: Observational

Funder types: Other

Identifiers

NCT05247944

1843

Details and patient eligibility

About

The aim of the present study was to investigate outcomes of a propensity matched series of patients treated with F-BEVAR and open surgery repair for complex abdominal aortic aneurysm in two aortic high-volume centres.

Full description

This retrospective study analyzes the long-term outcomes of a propensity-matched cohort of patients with complex abdominal aortic aneurysm prospectively collected between January 2010 and June 2016 from the Aortic Center of Lille (Lille, France) and the Unit of Vascular Surgery of Policlinic Gemelli (Rome, Italy).

Patients were observed with regular postoperative appointments. The long-term imaging follow-up consisted in a yearly computed tomography angiography in the F-BEVAR group; and yearly abdominal ultrasound examination and 5-year computed tomography angiography were performed in the open surgery repair group. In case of abnormal renal function (eGFR<60 mL/min/1.73 m2), the patient underwent computed tomography without contrast associated to a contrast-enhanced ultrasound examination in both groups. Laboratory data with evaluation of renal function by estimated glomerular filtration rate (eGFR), were completed at three, six, and 12 months, and yearly thereafter. Survival assessment was completed after general partitioner's, patients' or patient siblings' contact by phone.

Enrollment: 278 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• juxtarenal abdominal aortic aneurysms
• pararenal abdominal aortic aneurysms
• suprarenal abdominal aortic aneurysms
• type IV thoracoabdominal aneurysms

Exclusion criteria

• extent I to III thoracoabdominal aneurysms
• ruptured o symptomatic aneurysms
• dissections or connective tissue disorder aneurysms.

Trial design

278 participants in 2 patient groups

F-BEVAR

Description:

Patients with complex abdominal aortic aneurysm who underwent fenestrated and branched endovascular aortic repair (F-BEVAR) at the Aortic Center of Lille (ACL; Lille, France).

Treatment:

Procedure: Fenestrated and branched endovascular aortic repair (F-BEVAR)

OPEN SURGERY REPAIR

Description:

Patients with complex abdominal aortic aneurysm who underwent open surgery repair the Unit of Vascular Surgery of Policlinic Gemelli (FPUG; Rome, Italy).

Treatment:

Procedure: Open repair