Facial Serum and Mask and Ready-to-drink Jelly From Thai Rice

Burapha University

Status: Completed

Conditions: Rice Jelly; Rice Mask; Rice Serum

Treatments: Other: Study 3: Jelly with Hom Pathum rice; Other: Study 3: Jelly with Tubtim Chumpae rice; Other: Study 2: Facial mask with Hom Pathum rice extract; Other: Study 1: Facial serum with alpha albutin; Other: Study 3: Control jelly; Other: Study 1: Facial serum with Tubtim Chumpae rice extract

Study type: Interventional

Funder types: Other

Identifiers

NCT06475222

IRB1-047/2567

Details and patient eligibility

About

This study consisted of three sub-studies including 1) development and evaluation of facial serum from Thai rice on skin moisture, elasticity, oiliness, and melanin in healthy participants 2) development and evaluation of facial mask from Thai rice on skin moisture, elasticity, oiliness, and melanin in healthy participants and 3) development and evaluation of ready-to-drink jelly from Thai rice on controlling blood glucose and endurance time in healthy participants.

Full description

Study 1: 30 male and female participants, age 30-50 years will be randomly applied with facial serum producing from either 2% alpha albutin (standard facial serum) or Tubtim Chumphae rice extract on either right side or left side of their face daily for 12 weeks.

Study 2: 60 male and female participants, age 30-50 years will be randomly assigned into 2 groups including 1) control group (n = 30): participants will not receive any facial mask for 12 weeks and 2) treatment group (n = 30): participants will be applied with home-based program facial mask with Hom Pathum rice extract for 30 min/day, 2 days/week for 12 weeks.

Study 3: this study consists of 2 sub-studies. Study 3.1: 25 male and female participants, age 18-35 years will be randomly consumed with control jelly, jelly with Tubtim Chumphae rice, and jelly with Hom Pathum rice at 3.5 g/kg body weight. All participants will be measured for blood glucose levels before consumption and after consumption at 30, 60, 90, and 120 min. Study 3.2: 25 male and female participants, age 18-35 years will be randomly consumed with control jelly, jelly with Tubtim Chumphae rice, and jelly with Hom Pathum rice at 3.5 g/kg body weight. After each consumption, all participants will perform walking or running on treadmill at intensity of 80% maximal heart rate to measure maximal oxygen consumption.

Enrollment: 104 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male or female
• Age between 18 to 50 years
• Healthy
• Interested in facial serum with Thai rice extract or facial mask with Thai rice extract or jelly from with Thai rice

Exclusion criteria

• History of adverse effects from facial serum or mask application or jelly consumption
• Skin allergy
• Skin disorders
• Skin wounds
• History of allergy to Thai rice, particularly in Tubtim Chumpae and Hom Pathum
• History of allergy to facial serum or mask, i.e., serum or mask from rice
• History of allergy to gelatin
• Signs or symptoms of fever or infection
• Abnormal body mass index
• Regular smokers or alcohol drinkers (>2 times per week)
• Regular exerciser (>2 times per week or >150 min per week)
• Regular intake of dietary supplements, i.e., vitamins, antioxidants
• Hypertension, diabetes, cardiovascular disease, respiratory disease, endocrine disease, neuromuscular disease, musculoskeletal disease, liver disease, renal disease, immune disease, infectious disease, or cancer

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Double Blind

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104 participants in 6 patient groups

Study 1: Facial serum with alpha albutin

Active Comparator group

Description:

Participants will be randomly applied with home-based program of facial serum producing from 2% alpha albutin (standard facial serum) on either right side or left side of their face daily for 12 weeks.

Treatment:

Other: Study 1: Facial serum with alpha albutin

Study 1: Facial serum with Tubtim Chumpae rice extract

Experimental group

Description:

Participants will be randomly applied with home-based program of facial serum producing from Tubtim Chumpae rice extract on either right side or left side of their face daily for 12 weeks.

Treatment:

Other: Study 1: Facial serum with Tubtim Chumpae rice extract

Study 2: Facial mask with Hom Pathum rice extract

Experimental group

Description:

Participants will receive home-based program of facial mask with Hom Pathum rice extract for 30 min/day, 2 days/week for 12 weeks.

Treatment:

Other: Study 2: Facial mask with Hom Pathum rice extract

Study 3: Control jelly

Active Comparator group

Description:

Participants will consume with control jelly at 3.5 g/kg body weight. Consumption will be taken at Burapha University.

Treatment:

Other: Study 3: Control jelly

Study 3: Jelly with Tubtim Chumpae rice

Experimental group

Description:

Participants will consume with Tubtim Chumpae rice jelly at 3.5 g/kg body weight. Consumption will be taken at Burapha University.

Treatment:

Other: Study 3: Jelly with Tubtim Chumpae rice

Study 3: Jelly with Hom Pathum rice

Experimental group

Description:

Participants will consume with Hom Pathum rice jelly at 3.5 g/kg body weight. Consumption will be taken at Burapha University.

Treatment:

Other: Study 3: Jelly with Hom Pathum rice