"Facially Driven Digital Full-Mouth Rehabilitation"

Menoufia University

Status: Enrolling

Conditions: Malocclusion

Treatments: Device: Facially Driven, Fully Digital Full-Mouth Rehabilitation with Guided Implant Placement, TAD-Assisted Molar Intrusion, and Restorative Crowns/Veneers

Study type: Observational

Funder types: Other

Identifiers

NCT07314034

ADMNF-0051

Details and patient eligibility

About

Participants with bite difficulties, smile dissatisfaction, and missing mandibular molars was rehabilitated using a fully digital, facially driven workflow. Integration of intraoral, facial, and CBCT data guided esthetic design, occlusion, and implant planning, resulting in precise alignment, functional occlusion, and esthetic restoration with veneers, zirconia crowns, TAD-assisted molar intrusion, and guided implants.

Full description

This Prospective study describes the comprehensive digital management of patients presenting with anterior open bite, smile dissatisfaction, and missing mandibular molars. A 3D virtual patient model was created by integrating intraoral scans, facial scans, and CBCT imaging, enabling prosthetically driven planning for esthetic and functional outcomes. Treatment involved conservative anterior rehabilitation with lithium disilicate veneers, full-coverage monolithic zirconia crowns, TAD-assisted intrusion of extruded molars, and guided implant placement for missing mandibular molars. The fully digital, facially guided workflow allowed precise restoration positioning, occlusal harmony, and predictable functional and esthetic results, demonstrating the utility of integrated digital planning in complex full-mouth rehabilitation.

Enrollment: 10 estimated patients

Sex: All

Ages: 20 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults aged 20-45 years with partial or complete edentulism requiring full-mouth rehabilitation.
• Patients with bite dysfunction, malocclusion, or esthetic concerns suitable for digital workflow treatment.
• Adequate bone volume for implant placement or candidates for TAD-assisted tooth movement.
• Willingness to undergo treatment using a fully digital, facially guided workflow and comply with follow-up visits.
• Ability to provide informed consent.

Exclusion criteria

• Systemic conditions contraindicating implant or surgical procedures (e.g., uncontrolled diabetes, immunosuppression).
• Active oral infections or untreated periodontal disease.
• Heavy smokers (>10 cigarettes/day) or substance abuse.
• History of head and neck radiation therapy or bisphosphonate use.
• Pregnancy or breastfeeding.
• Inability to comply with treatment or follow-up protocol.