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Factors Associated With Clinical Outcomes in Patients Hospitalized for Covid-19 in GHT-93 Est

C

Centre Hospitalier Intercommunal Robert Ballanger

Status

Unknown

Conditions

SARS-CoV 2
COVID

Study type

Observational

Funder types

Other

Identifiers

NCT04366206
GHTRB-2020-01

Details and patient eligibility

About

Healthcare centers treated several hundreds of patients with Covid-19 and prospectively gathered information in electronic format between March, 2020 to April, 2020. In the course of Covid-19 treatment, physicians employed several drugs, including hydroxychloroquine, azithromycin, lopinavir/ritonavir, tocilizumab, baricitinib, sarilumab, corticosteroids and systematic antibiotics (list is not exhaustive).

This cohort study aims to assess factors associated with clinical outcomes in patients hospitalized for Covid-19, by analyzing associations between treatments and outcomes.

All data are collected in electronical records during routine practice.

Full description

Healthcare centers treated several hundreds of patients with Covid-19 and prospectively gathered information in electronic format between March, 2020 to April, 2020. In the course of Covid-19 treatment, physicians employed several drugs, including hydroxychloroquine, azithromycin, lopinavir/ritonavir, tocilizumab, baricitinib, sarilumab, corticosteroids and systematic antibiotics (list is not exhaustive).

This cohort study aims to assess factors associated with clinical outcomes in patients hospitalized for Covid-19.

Risk factors which will be studied include: baseline characteristics such as medical history and drugs with corresponding administration protocols.

Main outcomes include all-cause mortality, need for mechanical ventilation, for ICU transfer and all relevant biological syndromes.

All data are collected in electronical records during routine practice and additional data may be collected retrospectively.

Enrollment

143 estimated patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • hospitalized for Covid-19
  • severe pneumonia defined as pulse O2 < 96% despite > 6L/min

Exclusion criteria

  • lack of consent
  • palliative care patients
  • patients in ICU
  • patients transferred from ICU

Trial design

143 participants in 2 patient groups

Patients exposed to the study variable
Description:
Depending on the studied variable (treatment or risk factor)
Patients not exposed to the study variable
Description:
Depending on the studied variable (treatment or risk factor)

Trial contacts and locations

2

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Central trial contact

Hélène Gros, MD

Data sourced from clinicaltrials.gov

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