Factors Associated With Extubation Failure in Kanigara ICU (Intensive Care Unit) RSUPN Dr. Cipto Mangunkusumo

University of Indonesia (UI)

Status: Completed

Conditions: Ventilated Patients; Extubation Failure

Treatments: Other: Not applicable- observational study

Study type: Observational

Funder types: Other

Identifiers

NCT07038291

IndonesiaUAnes1006

Details and patient eligibility

About

Extubation is the final stage after patients undergo weaning procedure from mechanical ventilation in the ICU. Extubation failure followed by reintubation is associated with worse patient outcomes, including prolonged length of stay, increased risk of pulmonary infections, need for tracheostomy, higher healthcare costs, and increased mortality. Careful evaluation of various risk factors for extubation failure must be considered, therefore the extubation readiness guideline or checklist is essential before making the decision to extubate. This study aimed to identify factors associated with extubation failure in Kanigara ICU patients. This was a case-control study using secondary data from medical records of ICU patients who underwent extubation between January 2021 until August 2024. Variables analyzed included Glasgow Coma Scale (GCS) score, Arterial Blood Gas (ABG) results, hemodynamics, ventilator settings, airway protection ability, fluid balance, and airway-related problems. Bivariate and multivariate using logistic regression analyses were conducted to identify factors associated with extubation failure.

Enrollment: 156 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient age 18 years old or more were intubated in Kanigara ICU RSCM more than 24 hours

Exclusion criteria

• Dead or needed tracheostomy before extubation, or reintubated for surgical procedure

Trial design

156 participants in 2 patient groups

Extubation Failure

Description:

Patient with extubation failure

Treatment:

Other: Not applicable- observational study

Successful Extubation

Description:

Patient with successful extubation

Treatment:

Other: Not applicable- observational study