Factors Influencing Anesthetic Drug Requirement (PosoAnes)

Hopital Foch

Status: Completed

Conditions: Anesthesia, General

Treatments: Device: Closed loop anesthesia

Study type: Interventional

Funder types: Other

Identifiers

NCT00896714

2008/44

Details and patient eligibility

About

The main objective of the study is to analyze the influence of several environmental (i.e., timing: seasonal, circadian) and demographic conditions (i.e., age, gender, menstrual cycle) on anesthetic drug requirements (hypnotic and opiate).

Enrollment: 3,278 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing scheduled surgery under general anesthesia, agreeing to participate in the study

Exclusion criteria

• Age under 18 years
• Pregnancy, breastfeeding woman
• Allergy to propofol, soybeans or peanuts
• Allergy to sufentanil, remifentanil, morphine,
• Allergy to a muscle relaxant or to any of its excipients
• Known hypersensitivity to sufentanil, remifentanil, or to other derivates of fentanyl
• History of central neurological disorder or brain injury
• Patient with dementia
• Patient with pacemaker
• Patient receiving psychotropic drugs or morphine agonist-antagonists
• Surgery on the skull and/or operating position preventing the use of a bispectral index sensor in suitable conditions

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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3,278 participants in 1 patient group

Closed loop anesthesia

Experimental group

Treatment:

Device: Closed loop anesthesia