Factors Predicting Erythropoietin Responsiveness in Children on Hemodialysis at Sohag University Hospital

Sohag University

Status: Unknown

Conditions: Pediatric Patients on Hemodialysis

Treatments: Diagnostic Test: seum zinic,vit B12, parathyriod function

Study type: Observational

Funder types: Other

Identifiers

NCT05312346

Soh-Med-22-03-04

Details and patient eligibility

About

Anemia is common in patients on hemodialysis (HD) due to lack of erythropoietin (EPO) synthesis and iron deficiency is occurring in HD patients due to chronic blood loss through the dialysis circuit, repeated blood sampling, shortened red blood cell life span and lack of adherence to treatment .

Anemia is one of the most important complications that affects morbidity and mortality in chronic kidney disease (CKD) patients. It has significant impacts on those patients such as fatigue, weakness, shortness of breath, decreased quality of life, exercise capacity and physical activity, growth retardation and decreased cognitive functions, left ventricular hypertrophy, and congestive heart failure So, proper management of anemia is very important .

Enrollment: 50 estimated patients

Sex: All

Ages: 1+ year old

Volunteers: No Healthy Volunteers

Inclusion criteria

• (1) patients started dialysis in the age range of 1-18years. (2) Patient will be on regular hemodialysis.

Exclusion criteria

• Children who have no other co existent hematological disorder .

Trial design

50 participants in 1 patient group

responsiveness to erythropoietin stimulating agent

Description:

we evolute responsiveness of patients on hemodialysis for erythropoietin stimulating agents or not and factors effecting this response

Treatment:

Diagnostic Test: seum zinic,vit B12, parathyriod function