Factors Related to the Progression of Chronic Kidney Disease

Ankara Education and Research Hospital

Status: Unknown

Conditions: Chronic Kidney Disease

Study type: Observational

Funder types: Other

Identifiers

NCT01317173

NEPH001

Details and patient eligibility

About

Chronic kidney disease is a progressive disorder that has been influenced with many factors. Most of the patients has altered Ca P metabolism and these dis orders are the contributing factors of the disease progression. It has been recently documented that FGF23 and Klotho are the key factors of PTH secretion Ca-P metabolism. This study aimed to evaluate the impact of Klotho and FGF23 on the progression of stage 3-4 chronic kidney disease.

Enrollment: 90 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Non-diabetic chronic kidney disease

Exclusion criteria

• Presence of DM
• Actively using calcium based phosphorus binder of vitamin D

Trial design

90 participants in 2 patient groups

Progressive disease

Description:

Serum creatinin level rise more than 2 times

Non-progressive disease

Description:

Serum creatinin level rise less than 2 times