Family Motivational Intervention in Schizophrenia (FMI)

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Status: Unknown

Conditions: Schizophrenia; Cannabis

Treatments: Behavioral: Family Motivational Intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT01167556

Grant 100003014

Details and patient eligibility

About

Cannabis use by people with schizophrenia is associated with family distress and poor clinical outcomes. Therefore, an Family Motivational Intervention (FMI) was developed to help parents to motivate their child with a diagnoses of recent-onset schizophrenia to reduce cannabis use.

In a single-blind randomised clinical trail with 75 patients with the diagnosis of schizophrenia, parents will be assigned to either FMI or to routine care. Assessments will be conducted at baseline and at a 10- and 22-month follow-up. The study hypothesis is that FMI will be more effective than routine care in reducing (a) cannabis use in patients and (b) distress and sense of burden in parents.

Enrollment: 147 patients

Sex: All

Ages: 16 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of schizophrenia or psychotic-related disorder
• Onset of schizophrenia or related disorder within pervious the 10 years
• Cannabis use at least 2 days per week in the 3 months prior to the assessment
• Antipsychotic medication in prescribed or indicated
• At least 10 hours of contact with the parents each week in the last month

Exclusion criteria

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

147 participants in 2 patient groups

Family Motivational Intervention

Experimental group

Description:

An intervention provided to parents consisting of 6 sessions of training in Interactions Skills and 6 sessions training in Motivational Interviewing.

Treatment:

Behavioral: Family Motivational Intervention

Routine care for parents

Active Comparator group

Description:

Routine care for parents consisting of 2 sessions psycho-education and individual support

Treatment:

Behavioral: Family Motivational Intervention