Family Study of Lymphoproliferative Disorders

Mayo Clinic

Status: Enrolling

Conditions: Lymphoma, B-Cell; Multiple Myeloma; Monoclonal B-Cell Lymphocytosis; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT00626496

LS0587 (Other Identifier)

U01CA118444 (U.S. NIH Grant/Contract)

NCI-2021-14099 (Registry Identifier)

489-04

Details and patient eligibility

About

Blood and lymph node cancers can begin in either the lymphatic tissues (as in the case of lymphoma) or in the bone marrow (as with leukemia and myeloma), and they all are involved with the uncontrolled growth of white blood cells. There are many subtypes of these cancers, e.g., chronic lymphocytic leukemia and non-Hodgkin lymphoma. Since there is evidence that these cancers cluster in families, this study aims to understand how genetics and environmental exposures contribute to the development of these cancers.

Enrollment: 3,000 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

At least 2 living, blood related relatives, affected with a lymphoproliferative disorder.