Fast Titration in the Treatment of Schizophrenia, Taiwan

AstraZeneca

Status and phase: Completed; Phase 3

Conditions: Schizophrenia

Treatments: Drug: Quetiapine fumarate

Study type: Interventional

Funder types: Industry

Identifiers

NCT00304473

D1449C00001

Details and patient eligibility

About

Assess the efficacy of a fast titration of quetiapine to the current titration approved by the regulatory authorities.

PLEASE NOTE: Seroquel SR and Seroquel XR refer to the same formulation. The SR designation was changed to XR after consultation with FDA.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Signed informed consent, at least 18 years old, inpatients with relapse Schizophrenia all subtypes, and with a CGI (Clinical Global Impression) score >=4.

Exclusion criteria

• Pregnancy or breast-feeding, patients treated with Clozapine within 28 days of randomization, patients with a known arrhythmia, any psychotic disorders not defined in the inclusion criteria.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)