Fat Grafting in Skin-grafted Deep Burn Scars

Ghent University Hospital (UZ)

Status: Completed

Conditions: Burn Scar

Treatments: Procedure: lipofilling/ fat grafting; Procedure: placebo injection

Study type: Interventional

Funder types: Other

Identifiers

NCT03627650

EC 2010/ 572

Details and patient eligibility

About

fat grafting in human skin-grafted immature burn scars histological, clinical and photographic follow-up

Full description

Objective: A randomised clinical trial was performed to determine the effect of autologous fat grafting on scar formation in early skin-grafted deep burn wounds.

Methods: Included patients received split-thickness skin grafting procedures for deep burn wounds less than 3 months ago. A homogenous scar area in each patient was divided into two equal parts. One part was treated with transcutaneous sharp needle autologous fat grafting, the adjacent part with transcutaneous saline injection as control. Results were evaluated by clinical assessment with scar scale questionnaires, histological examination, and objective scar assessment with Cutometer, Mexameter, Tewameter and Corneometer.

Enrollment: 15 patients

Sex: All

Ages: 25 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• early skin-grafted deep burn scars
• otherwise healthy

Exclusion criteria

• concomitant disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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15 participants in 2 patient groups

1 group of 15 patients

Experimental group

Description:

procedure/surgery: fat grafting injection of scar

Treatment:

Procedure: lipofilling/ fat grafting

Same group of 15 patients

Experimental group

Description:

procedure/surgery: placebo injection of scar

Treatment:

Procedure: placebo injection